{"database": "canada-spends", "table": "cihr_grants", "rows": [["170247", "Control of sensory neuron development", "Chen  Hsiao-Huei", "Chen, Hsiao-Huei", "Ottawa Hospital Research Institute", "Ontario", "Canada", "200809", "300000.0", "CIHR New Investigator", "Salary Programs", "Biomedical", "Neurosciences, Mental Health and Addiction", "Electrophysiology; Experimental Embryology; Immunohistochemistry; Molecular Biology; Neurogenesis; Transgenic Mice", "Sensory neurons are frequently lost in patients with cancer, diabetes or HIV infection. Optimally, cell based therapies to\nselectively replace the missing sensory neurons will require knowledge of the molecular pathways controlling sensory\nneuron development and function. This knowledge may also be useful to treat other sensory neuropathies affecting hearing\nand vision. This proposal is directed at elucidating the signaling and transcription pathways that control development and\nfunction of sensory neurons that detect muscle stretch in the \"knee-jerk\" reflex. We have discovered a protein that is\nessential for these neurons to develop and survive. Using mouse models that lack this protein, we will dissect how this\nprotein works to control sensory neuron development.", "5 yrs 0 mth", "https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=170247&lang=en"]], "columns": ["external_id", "title", "project_lead_name", "co_researchers", "institution", "province", "country", "competition_year", "award_amount", "program", "program_type", "theme", "research_subject", "keywords", "abstract", "duration", "source_url"], "primary_keys": ["external_id"], "primary_key_values": ["170247"], "units": {}, "query_ms": 0.8905799986678176}