{"database": "canada-spends", "table": "cihr_grants", "rows": [["170393", "Novel tumour cell interactions in bone", "Ghert  Michelle A", "Ghert, Michelle A", "McMaster University", "Ontario", "Canada", "200809", "315643.0", "Operating Grant", "Operating Grants", "Biomedical", "Musculoskeletal Health and Arthritis", "Ap-1; Bone; Cytokine; Giant Cell Tumour; Mmp-13; Runx2", "The skeleton is very important for daily activities such as walking and posture. It is hence important for quality of life for an\nindividual. Cancers that primarily arise within the bone or that have spread to the bone can disrupt the architecture of the\nbone by altering the balance of bone formation and remodeling leading to overall bone destruction, pain and fracture. Giant\nCell Tumour of bone is an aggressive bone tumour that typically affects young adults and requires extensive surgery for\ncure. Dr. Ghert's lab has done extensive research exploring the mechanisms involved in the destruction of bone by these\ntumours. The overall goal of Dr. Ghert's research is to develop effective targeted molecular treatment for cancers that affect\nbone in which bone formation and destruction are imbalanced.", "3 yrs 0 mth", "https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=170393&lang=en"]], "columns": ["external_id", "title", "project_lead_name", "co_researchers", "institution", "province", "country", "competition_year", "award_amount", "program", "program_type", "theme", "research_subject", "keywords", "abstract", "duration", "source_url"], "primary_keys": ["external_id"], "primary_key_values": ["170393"], "units": {}, "query_ms": 0.43229600123595446}